The following information contains a number of recommendations when caring for a patient with a VAD, aimed at improving patient safety and reducing the risk of harm.

Principle Rationale and action
VAD inspection

The VAD should be checked and observed every time the device is being used. If the VAD is not being used for continuous infusions, then the patency of the device should be assessed as frequently as required for the VAD and prior to any medicine administration, transfusions or other infusions.

Frequency of VAD checks by a healthcare practitioner is dependent on clinical area, patient’s clinical condition and types of IV medicines being administered e.g. patients receiving irritant medications may have increased frequency checks and patients in community setting may have a decreased frequency of checks.  Observation should include:

  • Insertion point and surrounding areas - are there any signs of inflammation, phlebitis, infection, infiltration or extravasation?
  • Dressing – is it clean, dry and intact?
  • Integrity of VAD – does the VAD show signs of leakage (fluid or air escaping) or any visible fractures/cracks?
  • Security of connections – is the VAD and connections secure? Is there evidence of leakage from connections? If fixation device or sutures used, do these look secure?
  • Dislodgment or migration of device – does the VAD look as if it has moved, dislodged or migrated from its previous position?

All checks and actions should be clearly documented.

Dressings

If the dressing is loose, damp or soiled, it should be replaced immediately, and the patency of the VAD should be assessed. 

Ideally all central VADs should have a chlorhexidine impregnated dressing or patch placed over the exit site to reduce the risk of catheter related bloodstream infection. This includes PICCs, non-tunnelled and tunnelled central venous catheters and dialysis catheters.
Dwell times

All VADs should be removed when no longer clinically indicated.  VADs may remain in situ for as long as required unless there is a clinical for removal and there are no signs of phlebitis or infection.

Maximum dwell times should be in line with manufacturer’s recommendations.

Medical and nursing staff should review the need for intravenous therapy, including antibiotics, on a daily basis and consider IV to oral switch over, if appropriate.

Aseptic non-touch technique® (ANTT) A framework that promotes safe and effective aseptic technique for clinical procedures which is based on the principles of Rowley (2010). The Aseptic Non Touch Technique (ANTT®) Guideline has specific guidance and picture templates for procedures. See teaching materials on ward for ANTT.
Standard infection control precautions Current local and national guidance advise that Standard Infection Control Precautions (SICPs) should be embedded into all aspects of care delivery including the care of patients with VADs. Practitioners are expected to adhere to the principles of SICPs to reduce patient harm.
Needle free access devices (NFADs)

The purpose of a NFAD is to facilitate accessing a VAD during the administration of single or multiple IV infusions, reduce the risk of catheter related blood stream infections (CRBSI) and needle stick injuries. NFADs should be attached to VADs, unless these connectors are inappropriate for use with a particular VAD.

All needle free access devices, whether single or multiple, with or without extension sets, must be primed before use with sterile IV 0.9% sodium chloride solution.  

There are a huge variety of different NFADs available and clinical specialities/practitioners should determine the NFAD appropriate to the patient’s need and VAD requirements. Anti-reflux valve NFADs are also available and should be considered for use when high risk for extravasation medications and therapies are being administered.

NFADs should be changed according to manufacturer’s advice unless there is a clinical rationale to increase the frequency.

*Some clinical areas may have a rationale to change NFAD more frequently than manufacturer’s recommendations e.g. every 72 hours.

A PVC must always have a NFAD with extension set attached to avoid inadvertent mechanical phlebitis when attaching and disconnecting to the NFAD (*with an exception in theatres, endoscopy and imaging). 

‘Scrub the hub’ of the NFAD for at least 30 seconds using 2% chlorhexidine and 70% isopropyl alcohol wipe and allow to dry before attaching syringes or administration sets.
Port protectors (*alcohol impregnated) Disinfecting port protectors may be considered as part of a care bundle/strategy to reduce the risk of CRBSI. When removing a port protector to connect an administration set or syringe, the NFAD end should still be decontaminated with 2% chlorhexidine in 70% isopropyl alcohol wipe (‘scrub the hub’) for a minimum of 30 seconds and allow to dry.
Flushing of VADs A flush is normally sterile 0.9% sodium chloride solution. All flush solutions should be independently checked with a registered healthcare practitioner. The necks of flush ampoules or vials should be decontaminated with 2% chlorhexidine in 70% isopropyl alcohol. Flush solution should be drawn up using a blunt filter needle or a 23g safety hypodermic needle and a 10ml luer lock syringe, or larger. A turbulent push-pause flush with sterile 0.9% sodium chloride (NaCl) finishing with positive pressure is required to maintain catheter patency. The volume of flush will vary depending on the patient, VAD and NFAD in use.
Locking of VADs

Evidence-based research recommends that using a turbulent push-pause flush with sterile 0.9% sodium chloride (NaCl) in a 10ml syringe (or larger) finishing with positive pressure is sufficient to maintain catheter patency and ‘lock’ VADs.

In regard to CVAD’s, locking of the catheter may require taurolock or heparin. This will be detailed in each child’s care plan.
Blood discards

Blood discards are small volumes of blood withdrawn to ensure patency and placement of the tip of the VAD. This small sample is frequently referred to as a ‘blood discard’ as it is not used for therapeutic monitoring purposes, except for blood cultures. Discard volumes should be dependent on required investigations and should be discussed with medical staff. Small blood volume losses from repeated blood discards can have an accumulative effect and can become particularly significant in infants and small children where total blood volume is much less overall.  In this situation, consideration should be given to the volume discarded and the overall impact this may have and whether the blood needs to be discarded or returned.

If a catheter locking solution is used, at least 2mls discard should be taken every time the line is accessed to ensure the solution is removed.

Maximum blood discard should be 3-5mls to reduce iatrogenic blood loss (Lalthanthuami et al., 2021).
Parenteral nutrition VADs may be inserted for multipurpose use. This may require that VADs used for administration of parenteral nutrition, may also require to be used for administration of other medications, therapies or blood sampling. This is done on an individual/case-by-case review and risk assessment undertaken and documented by the multi-disciplinary team and is due to the limited availability of vascular access.
Blood sampling from VADs

Within NHSA&A, blood samples are routinely obtained using venepuncture equipment and a peripheral blood sample. In certain circumstances, some VADs may be used to obtain blood samples. The decision-making process is complex and multifactorial. 

When considering using a VAD to obtain blood samples, it is crucial to consider the potential increased risk of infection when accessing the VAD over increased skin punctures from multiple venepuncture attempts. Some VADs are inserted with particular purpose in mind. For example, patients undergoing long term chemotherapy treatment with difficult intravenous access may have a CVAD inserted to avoid multiple cannulations and venepunctures - it may be appropriate to sample from the VAD. Blood sampling from VADs must only be undertaken by registered healthcare practitioners, competent to do so.

Blood sampling for therapeutic monitoring is not recommended from a VAD that is being used to deliver medications as this will affect the results. Established PVCs and below antecubital fossa midlines should not be used for blood sampling. Blood sampling from VADs should be discussed with the medical staff and nurse specialists prior to the procedure.
Administration sets When an administration set is connected to a VAD, it is essential, that a closed system is maintained, avoiding unnecessary disconnection. The choice and selection of the appropriate NFAD is important as a multiple lumen NFAD would prevent many unnecessary disconnections. When the closed system is interrupted it is essential to observe an aseptic non touch technique (ANTT®). Administration sets are single use and should be discarded once disconnected and after 24 hours of use in continuous infusions. In some clinical situations, it may not be possible to avoid disconnection of administration sets due to the type of treatment being administered to the patient. The practitioner should assess the rationale for the disconnection. If it is essential for patient care that the treatment/equipment cannot be disposed of, an ANTT® procedure should be adhered to and the VAD should be flushed appropriately with sterile 0.9% sodium chloride (NaCl), and the administration set sealed with a sterile curos cap.
Allergy

Patient’s allergies must be checked prior to any procedure from a dressing, topical solutions and medicines perspective. If the patient has a chlorhexidine allergy, alcoholic povidone-iodine solution can be used instead of 2% chlorhexidine in 70% isopropyl alcohol. 

2% chlorhexidine in 70% isopropyl alcohol cannot be used in neonates less than 32 weeks gestation who are less than 7 days old. Refer to local guidelines for further advice. 0.5% chlorhexidine in 70% isopropyl alcohol is recommended as an alternative for babies less than 3 months old.
Medicines prescription All medicines must be prescribed as appropriate. This may be on an approved electronic system or paper medicine prescription chart. It is authorised practice in paediatrics for a flush not to be prescribed. However, the volume of the flush should be recorded in the documentation.