There is a clear association between frailty and polypharmacy. Assessment of frailty should be considered when individuals are taking 10 or more multiple medications or have two or more long-term conditions. It is important to acknowledge that multimorbidity can occur earlier in those from more deprived backgrounds. Any interaction between a health or social care professional and an older person, aged over 65 should include an assessment of frailty. Assessment of clinical frailty can indicate how a person may respond to treatment, or about their future healthcare needs. It may highlight reversable causes of frailty.