Investigating and managing diabetes in children (Type 1 & Type 2) (Paediatric Guidelines)

Warning

Audience

  • North NHS Highland only
  • Primary and Secondary Care 
  • Paediatrics only

Possible Type 1 Diabetes: 

  • Thirsty, Tired, Toilet, Thinner
  • Think, Test, Telephone today

Type 1 screening primary care

If type 1 diabetes is suspected:

  • Please check a capillary blood glucose IMMEDIATELY and, if elevated, phone the On-Call paediatric team for admission that day.

If the child has symptoms of diabetes (polyuria, polydipsia, weight loss and lethargy) but has reduced oral intake, has been vomiting or bloods have been taken before breakfast, they may have a normal blood glucose.

  • Therefore, if the clinical suspicion is high, DO NOT be reassured by a normal glucose level. Please refer in, as, on the ward, the child can be given a high glucose meal or drink and blood glucose testing repeated.
  • Other signs of type 1 diabetes can include fungal infections, such as thrush and balanitis over the age of 1 year, and should prompt testing.
  • A urine sample tested for glucose can be useful but is often harder to obtain in the younger child and can give falsely reassuring results. So, as above, if the clinical suspicion is high, please refer the same day.

NOTE: Fasting glucose, laboratory glucose or HbA1c are NOT suitable investigations, and delay diagnosis, increasing the chance of patients developing DKA while waiting for tests and results.

Type 2 screening primary care

Screening for type 2 diabetes in young people under 16 years (based on ISPAD guidelines 2022)

Undiagnosed type 2 diabetes is rare in the adolescent population, even among high risk individuals. Generalised population screening of obese youth is therefore unlikely to be cost effective in most populations.

Testing to identify clinical cases of diabetes SHOULD be considered in obese children and adolescents (BMI > 85th centile for age and sex) after 10 years of age who have the following risk factors for diabetes:

  • First or second degree family history of type 2 diabetes
  • Maternal history of type 2 diabetes or gestational diabetes during child’s gestation
  • High risk ethnicity (south east Asian/afro-Caribbean/middle eastern background)
  • History, symptoms or signs of insulin resistance (polycystic ovarian syndrome, acanthosis nigricans, hypertension, dyslipidaemia, obstructive sleep apnoea, low birth weight or small for gestational Age)

Other co-morbidities of obesity such as metabolic dysfunction-associated steatotic liver disease (MASLD), dyslipidaemia, elevated BP and PCOS (polycystic ovary syndrome) are more prevalent than dysglycaemia and SHOULD be screened for if Type 2 diabetes is being considered.

Type 2 diabetes can be diagnosed using an HbA1c.

  • Please ensure the request form says 'suspected Type 2 diabetes’, NOT Type 1, otherwise the laboratory may not process it as it would be an inappropriate test for possible Type 1 diabetes.

If the HbA1c is ≥ 48 mmol/mol in a patient suspected of type 2 diabetes:

  • Contact the on-call paediatric team
  • They will admit the patient and arrange investigations to confirm diabetes type and the paediatric diabetes team will review.

Secondary care management

Initial management of a child presenting with diabetes: 


The newly diagnosed child with Type 1 diabetes: 

Initial investigations

The following bloods need to be checked at diagnosis:

  • Lab Glucose – one yellow Fluoride Oxalate tube
  • Coeliac antibodies, anti-GAD, IA2, ZnT8 antibodies – 2 white clotted/serum tubes
  • Thyroid function tests – one paediatric white tube (or adult brown tube)
  • HbA1c – one red EDTA tube

Initial management

If the child is well and not in DKA at presentation, start them on basal bolus therapy with FIASP and LANTUS.  Do not wait for laboratory glucose to come back before starting treatment.  If the child presents out with meal times, they should have a correction dose of FIASP.

Starting doses 0.6u/kg/day if ketones ≤ 1.0 at presentation

                          0.8u/kg/day if ketones >1.0 at presentation

Prescribe 50% as the basal insulin LANTUS.  Please prescribe it for 9pm.  Prescribe this on the basal or long acting insulin page on the front of the prescription.

Prescribe the remaining 50% as FIASP, approximately split into 3 equal doses before breakfast, lunch and tea.  If breakfast is usually minimal or missed, the amount of insulin for that meal should be adjusted accordingly.  Prescribe this in the rapid acting insulin section on the 2nd page under ‘fixed doses’.  Older children of secondary age should be prescribed a dose of FIASP for their evening snack at 9pm (to coincide with correction dose before bedtime).  If so please prescribe FIASP insulin at one third of the evening meal dose for 9pm.

Remember to complete the whole prescription, which includes calculating both the standard correction dose and the ketone correction dose.  These are calculated based on the total daily dose of insulin.  This is on the bottom of page 2 of the prescription chart.   From this the initial correction dose can be given.

Adjusting Doses

Blood sugars should be checked before main meals and before the bed time snack.

The starting doses above will most likely need to be changed during the admission. 

If for example the child is high before breakfast, increase the evening Lantus dose by 10%.  If high before lunch, increase the morning FIASP dose by 10% etc. 

Similarly, if the child is hypo, or less than 5 on wakening, reduce the Lantus dose by 10%. 

The diabetes team will do this on weekdays, but please review during the weekend ward rounds and make adjustments as necessary.

Dietary management

Diet is an essential part of diabetes treatment. A well balanced diet will help control blood sugars and maintain a healthy weight. The dietitian will see patients at diagnosis to provide individual advice.

Meals

Although individual dietary advice can depend on insulin regime, it is important to have starchy carbohydrates at each meal such as potatoes or wholemeal versions of bread/pasta/rice/noodles plus some protein and fruit or vegetables. Sugary drinks and snacks should be avoided.

Snacks

Children on basal bolus therapy do not need to snack between meals, but if they wish could have a small carbohydrate snack between meals.

A piece of fruit is the ideal snack between meals. Other options include a pancake, plain biscuit, crackers, natural yoghurt, toast or bread. Sugary drinks and snacks should be avoided.

Initial education

The family should be provided at admission with their own copy of the locally prepared folder “Your Guide to Diabetes” (on the intranet under the title “introduction to diabetes”). The pages on “introduction to diabetes” and “life with diabetes” are printed in duplicate in the booklet to allow family members to share, and are likely to be particularly useful in setting realistic expectations from the outset.

Aims of the admission

The aim of the admission is not stability. Even if the blood sugars were perfect on going home, the change in routine would require early adjustment of insulin doses. The target is that the child should have blood ketone levels less than 1 mmol/L, and that the parents should be confident in giving injections, blood glucose testing, recording sugars, recognising and treating hypoglycaemia and knowing to call for advice as necessary. The diabetes team will maintain close telephone contact in the first few weeks to help with dose adjustment.


Diabetic ketoacidosis (DKA): Paediatric DKA integrated care pathway: 

  • All children admitted with DKA should be admitted to paediatric HDU and the on-call consultant informed.
  • Please print out and follow: BSPED DKA Guidelines | BSPED
  • In addition to investigations outlined in the DKA protocol, the following bloods also need to be checked at diagnosis: (1 yellow, 3 white, 1 red paediatric tubes)
    • Lab glucose. one yellow fluoride oxalate tube
    • Coeliac antibodies and anti-GAD/IA2/ZnT8 antibodies, 2 white clotted/serum tubes
    • Thyroid function tests, one white tube or adult brown tube
    • HbA1c, one red EDTA tube

Abbreviations

BMI: Body Mass Index
BP: Blood Pressure
BSPED: British Society for Paediatric Endocrinology and Diabetes
DKA: Diabetic Ketoacidosis
EDTA: Ethylenediaminetetraacetic Acid
GAD: Glutamic Acid Decarboxylase (Antibody)
HbA1c: Haemoglobin A1c
HDU: High Dependency Unit
IA2: Islet Antigen-2 (Antibody)
ISPAD: International Society for Paediatric and Adolescent Diabetes
MASLD: Metabolic Dysfunction-Associated Steatotic Liver Disease
PCOS: Polycystic Ovary Syndrome
ZnT8: Zinc Transporter 8 (Antibody)

Editorial Information

Last reviewed: 31/03/2026

Next review date: 31/03/2029

Author(s): Paediatrics.

Version: 2

Approved By: TAM subgroup of the ADTC

Reviewer name(s): Dr V Franklin, Consultant.

Document Id: TAM746